Thalassemia, also called
Mediterranean anemia, is a form of inherited autosomal recessive blood disorder
characterized by abnormal formation of hemoglobin. The abnormal hemoglobin
formed results in improper oxygen transport and destruction of red blood cells.
Thalassemia is caused by variant or missing genes that affect how the body
makes hemoglobin, the protein in red blood cells that carries oxygen. People
with Thalassemia make less hemoglobin and have fewer circulating red blood
cells than normal, which results in mild to severe microcytic anemia.
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